Casey S. Greene, PhD, is the Marsico Chair in Excellence in Biomedical Information Technology, Chair and Professor in the Department of Biomedical Informatics, and Director of the Colorado Center for Personalized Medicine. He is a leader in healthcare AI, personalized medicine, biomedical informatics, and academic medicine whose work uses machine learning, genomics, and large-scale clinical and biological data to improve discovery and patient care. At CU Anschutz, Casey leads interdisciplinary efforts spanning biomedical informatics, translational research, and data-driven healthcare. His lab develops AI and data science methods that integrate diverse large-scale datasets to extract clinically and biologically meaningful patterns, with a focus on precision medicine, translational genomics, and the responsible use of biomedical data. In addition to advancing computational methods, a core mission of his lab is bringing these capabilities into every molecular biology and medicine environment through open, transparent science conducted by a diverse team of researchers. Before starting the Integrative Genomics Lab in 2012, Casey earned his Ph.D. for his study of gene-gene interactions in the field of computational genetics from Dartmouth College in 2009 and moved to the Lewis-Sigler Institute for Integrative Genomics at Princeton University where he worked as a postdoctoral fellow from 2009-2012. The overarching theme of his work has been the development and evaluation of methods that acknowledge the emergent complexity of biological systems.